What is Percocet 5/325 (Oxycodone and acetaminophen)?
Percocet 5/325 (Oxycodone, acetaminophen) contains a combination of acetaminophen and oxycodone. Oxycodone is an opioid pain medication. An opioid is sometimes called a narcotic. Acetaminophen is a less potent pain reliever that increases the effects of oxycodone.
Percocet 5/325 (Oxycodone and acetaminophen) is used to relieve moderate to severe pain.
You should not use Percocet if you have recently used alcohol, sedatives, tranquilizers, or other narcotic medications.
This medicine can slow or stop your breathing, and may be habit-forming. Use only your prescribed dose, and swallow the pill whole to avoid a potentially fatal dose. Never share Percocet with another person.
MISUSE OF THIS MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.
Do not use Percocet 5/325 (Oxycodone and acetaminophen) if you have used a MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.
Do not take more Percocet than is recommended. An overdose of acetaminophen can damage your liver or cause death. Call your doctor at once if you have nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes).
Oxycodone may cause life-threatening withdrawal symptoms in a newborn if the mother has taken this medicine during pregnancy.
An overdose of acetaminophen can damage your liver or cause death. Call your doctor at once if you have nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes).
Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.
Fatal side effects can occur if you use this medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing.
Before taking this medicine
You should not use Percocet if you are allergic to acetaminophen (Tylenol) or oxycodone, or if:
you have severe asthma or breathing problems;
you have a blockage in your stomach or intestines, including paralytic ileus; or
you have recently used alcohol, sedatives, tranquilizers, or other narcotic medications.
Some medicines can interact with oxycodone and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take medicine for depression, mental illness, Parkinson’s disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.
To make sure Percocet 5/325 (Oxycodone and acetaminophen) is safe for you, tell your doctor if you have:
any type of breathing problem or lung disease;
liver disease, cirrhosis, or if you drink alcohol daily;
a history of drug abuse, alcohol addiction, or mental illness;
kidney disease, urination problems;
problems with your gallbladder, pancreas, thyroid, or adrenal gland;
a history of head injury, brain tumor, or seizures;
if you use a sedative like Valium (diazepam, alprazolam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Versed, Xanax, and others).
Percocet is more likely to cause breathing problems in older adults and people who are severely ill, malnourished, or otherwise debilitated.
If you use oxycodone while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.
Acetaminophen and oxycodone may pass into breast milk and could harm a nursing baby. You should not breast-feed while using this medicine.
How should I take Percocet?
Take Percocet exactly as prescribed. Follow all directions on your prescription label. Oxycodone can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed. Never use Percocet in larger amounts, or for longer than prescribed. An overdose can damage your liver or cause death. Tell your doctor if the medicine seems to stop working as well in relieving your pain.
What should I avoid while taking Percocet?
Do not drink alcohol. Dangerous side effects or death could occur.
See also: Percocet and alcohol (in more detail)
Percocet may impair your thinking or reactions. Avoid driving or operating machinery until you know how this medicine will affect you. Dizziness or severe drowsiness can cause falls or other accidents.
Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose.
Percocet side effects
Get emergency medical help if you have signs of an allergic reaction to Percocet: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking Percocet and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.
Like other narcotic medicines, oxycodone can slow your breathing. Death may occur if breathing becomes too weak.
Call your doctor at once if you have:
shallow breathing, slow heartbeat;
a light-headed feeling, like you might pass out;
confusion, unusual thoughts or behavior;
problems with urination;
infertility, missed menstrual periods;
impotence, sexual problems, loss of interest in sex;
liver problems – nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
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